Dioplus 5/160mg Tablet 14s

The mechanism of action of Valsartan 160mg, Amlodipine 5mg Tablet involves a dual mechanism to manage high blood pressure and heart-related conditions. Valsartan, an angiotensin II receptor blocker (ARB), works by blocking the action of angiotensin II, a potent vasoconstrictor, at its receptor sites. This blockade results in vasodilation, reducing blood pressure and decreasing the workload on the heart. On the other hand, Amlodipine, a calcium channel blocker (CCB), inhibits the influx of calcium ions into vascular smooth muscle cells and cardiac muscles. This inhibition leads to relaxation of vascular smooth muscles, causing a decrease in peripheral vascular resistance and blood pressure. The combined effect of Valsartan and Amlodipine provides a synergistic action, resulting in improved blood pressure control, reduced cardiovascular risk, and alleviated symptoms of heart failure.